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OLYMPUS BRONCHOSCOPE


   Johns Hopkins Hospital is alerting 415 patients and their families that a defective medical instrument may have given them a potentially life-threatening lung infection. The instrument, made by Olympus AMerican, was used to perform bronchoscopies, which inspects a patient's lungs and take tissue samples.

   A thin, tube-like instrument, about the width of a pencil, is placed through the nose or mouth and into the lungs. The tube has a tiny camera at the tip and uses fiber-optic technology to produce pictures of airways. Some patients who were examined by one of three contaminated bronchoscopes have died.

   Hospital officials discovered the problem after realizing that 128 patients had been infected with a bacterium known as pseudomonas. The number was two to three times higher than the hospital would expect, said Dr. Paul J. Scheel Jr., vice chairman of medicine.

   Hospital officials told The Sun of Baltimore in Sunday editions that they have not determined how many patients have been infected or died but have sent certified letters warning 415 patients. Those at risk include anyone who had a bronchoscopy procedure between June 1, 2001, and Feb. 4, 2002, the letter says.

   The letter asks patients to call their doctors if they experience symptoms that include fever, coughing, phlegm or shortness of breath. The national Centers for Disease Control and Prevention and the Food and Drug Administration are investigating the problem, in part to determine if the device has triggered outbreaks elsewhere, The Sun reported.

   The recall letter to Hopkins, dated Nov. 30, wasn't immediately acted on because it was mistakenly addressed to the loading dock of the Hopkins physiology department, the paper said.In recall letters, Olympus described the defective instruments as having a loose valve that trapped bacteria.

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