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HOME --- DEFECTIVE DRUGS --- REZULIN
On March 21, 2000 head of the FDA's center for Drug evaluation and Research stated that the "Continued use of Rezulin" posed an "unacceptable risk " to diabetes patients. At least 63 Rezulin users have died of liver failure. The total number of deaths is estimated to be as many as ten times higher than the reported 63 cases.
Doctors prescribed Rezulin to diabetics who took insulin but whose blood sugar was not well controlled. It was designed to help insulin (either your own or injected) work better, by drawing the sugar from your blood into the cells to supply energy.
Rezulin was approved for diabetics who used insulin and took certain types of oral antihyperglycemic medications or fodiabetics.
The patients diabetes could not be controlled by diet and exercise alone.
Rezulin was banned in England in December 1997, following the death of an American who took the drug. The drug manufacturer, Warner-Lambert successfully fought a ban in the U.S. for 27 months before the FDA decided to prohibit sales of the drug on March 21, 2000.
Before the ban, sales of Rezulin generated Warner-Lambert $1.8 billion in revenues. At its peak, the drug was prescribed 488,000 times in January of 1999. 63 Rezulin users have reportedly died from use of the drug. The deaths were caused by liver failure. The total number of deaths is likely to exceed 63 by many times according to experts.
Other Names:
Troglitazone
Adverse Effects/
Potential Injuries:
Liver Failure
Liver Disease
Liver Transplant
Jaundice
Related Terms:
Diabetes Drug
Adult Onset Diabetes
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