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Fen-Phen Related Side Affects....
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In 1997 the FDA asked American Home Products, a the maker of Pondimin (Fenfluramine) and Redux (Dexfenfluramine), to withdraw it's popular anti-obessity drugs from the market. American Home Products Corp. of Madison, N.J., manufactured fenfluramine under the brand name Pondimin and a American Home Product's subsidiary Wyeth-Ayerst Laboratories, manufactured Dexfenfluramine for Interneuron Pharmaceuticals, which was marketed under the name of Redux. Medical studies have linked Pondimin or Redux to heart valve.
The FDA stated that in findings from doctors who evaluated patients that took Fenfluramine and Dexfenfluramine, with echocardiograms, that approximately 30 percent of patients who were evaluated had abnormal echocardiograms, even though they had no symptoms. This is a much higher than expected percentage of abnormal test results.
Additionally a Mayo Clinic study that was published in the New England Journal of Medicine on August 28, 1997 suggested that as high as one-third of a patient sampling of Fen-Phen diet pill users had evidence of heart valve disease. The study found that there was a high incidence of heart valve disease in patients taking these diet pills, without any other known reason for valve disease.
In addition to heart valve disease the use of fenfluramine and dexfenfluramine has been found to increase the risk of developing Primary Pulmonary Hypertension or (PPH). PPH is a rare disease of that causes the progressive narrowing of the blood vessels of the lungs. Studies estimate that treatment with certain appetite suppressant drugs tends to increase the chances of developing PPH by approximately 25 to 30 percent.
Other Names:
Redux
Pondimin
Fenfluramine
Dexfenfluramine
Adverse Effects/
Potential Injuries:
Primary Pulmonary Hypertension (PPH)
Atrial Valve Regurgitation
Mitral Valve Regurgitation
Atrial Valve Prolapse
Mitral Valve Prolapse
Related Terms:
Fastin
Adipex
Phentermine
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